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Among all DEGs in the TGF signaling pathway, TXNDC5 showed the most significant downregulation in the kidneys of Usp2 KO mice compared to WT mice, as determined by RNA-seq analysis (Fig

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Overall, the median (Q1 to Q3) age of patients at baseline was 57 (49 to 65) years, 57% were female, 18% were Hispanic, 68% were White, 27% were Asian, and 0.6% were Black or African American

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